Answers to your questions about DIASTAT and seizures
For people with seizures and those who care for them

Your doctor has recommended DIASTAT to help you control some of your seizures. DIASTAT is given by a caregiver, usually a relative, spouse or friend who is familiar with you and your seizure patterns.

Below are common questions that people with seizures and their caregivers have about DIASTAT.

What is DIASTAT?
DIASTAT is a unique gel formulation of diazepam. It is the only FDA-approved at-home medication for the treatment of serial or cluster seizures, sometimes referred to as acute repetitive seizures. DIASTAT is an easy and painless way to control seizure episodes (clusters).

When should DIASTAT be given?
DIASTAT should be given for serial or acute repetitive seizures. During these episodes, one seizure ends and another follows soon after. This pattern is difficult to stop and often results in a trip to the emergency room (ER). By giving DIASTAT, you may stop the seizure and avoid a trip to the ER.

How soon should seizures stop after giving DIASTAT?
The seizures usually stop within 5 to 15 minutes. If seizures continue, your caregiver should call for medical help.

Why should I use DIASTAT? Isn’t it better to go to the emergency room?
Making trips to the ER every time you have a seizure can be very stressful for you and your family. It can also be costly. Families of people who use DIASTAT have had positive experiences. They are able to control these episodes with less stress on everyone involved. By using DIASTAT, you can stop seizures quickly and safely.

What if I have seizures and need DIASTAT when I am away from home?
DIASTAT can be taken with you, wherever you go – the office, on vacation, anytime you are away from home. It does not need to be refrigerated. DIASTAT should not be kept where it might get too hot or too cold, like the trunk of your car. Keep DIASTAT in a place that is easy to get to when you need it.

Does the caregiver giving DIASTAT need special training?
The caregiver should read and thoroughly understand the dosing instructions prior to administration. Your healthcare provider will give this information to you and your caregiver. After giving DIASTAT, your caregiver must stay with you to make sure that you are well enough to return to your usual activities.

If DIASTAT stops my seizures, do I still need to take my other seizure medications?
Yes. DIASTAT cannot take the place of your other medications. Do not stop taking any other medications without first speaking with your doctor.

What is the right dose for me?
DIASTAT comes in prepackaged, prefilled, and premeasured doses for children and adults. Your doctor has prescribed the one that is right for you. Let your doctor know if your weight or height changes, because your dose may need to be changed.

Why is DIASTAT administered rectally?
When you are experiencing a seizure, taking medications can be difficult. You may not be able to swallow a pill, or it might cause you to choke. Other medications may require administration by a medical professional. DIASTAT can be given by your caregiver wherever you are. Rectal absorption of DIASTAT is rapid, safe, and effective. In fact, because of its rapid absorption, rectal administration is very common worldwide.

What kinds of side effects can I expect?
DIASTAT has been safely used in children and adults ranging in age from 2 years to 76 years. The most common side effect with DIASTAT is sleepiness. Other less frequent side effects include skin rash, dizziness, pain, headache, stuffy nose, abdominal pain, nervousness, diarrhea, feeling unsteady or clumsy, and wheezing. You or your caregiver should tell your doctor about any side effects that you experience with DIASTAT.

When should I call for emergency help?
Your doctor or nurse may have told you about situations when medical help may be needed. For instance, if, after DIASTAT is given:
  • Seizure(s) continues 15 minutes after giving DIASTAT
  • Seizure behavior is different from other episodes
  • You are alarmed by the frequency or severity of the seizure(s)
  • You are alarmed by the color or breathing of the person
  • The person is having unusual or serious problems

    What should I do if I have more questions?
    Always speak with your healthcare provider about any questions you may have. To make sure you don’t forget your questions, you may want to write them down and bring them with you to your next appointment. These questions and answers have been designed to provide you with information about DIASTAT, they do not address every aspect of treatment. If you have other questions or concerns, please talk with your doctor, nurse, or pharmacist.